Drugs are manufactured or characteristic synthetic substances that can be found in professionally prescribed medications, over-the-counter remedial medications and veterinary medications. Drugs contain dynamic fixings that have been intended to have pharmacological impacts and give critical advantages to society. Drugs can be brought into water sources through sewage, which conveys the excreta of people and patients who have utilized these synthetic compounds, from uncontrolled medication removal (for example disposing of medications into latrines) and from farming overflow including animals fertilizer. They have become synthetic substances of developing worry to the public due to their capability to arrive at drinking-water. Numerous sorts of drug substances have been distinguished with critical focuses through different progressed instrumental methods in surface water, subsurface water, ground water, homegrown waste water, metropolitan waste water and mechanical effluents. The focal just as state governments in India are giving backings by making extract obligation free zones to advance the drug makers for their creation. Therefore, drug organizations are delivering various sorts of drug items everywhere scale and furthermore creating complex non-biodegradable harmful materials side-effects and delivering untreated or incompletely treated squanders in the climate without solid guidelines. These waste toxins are tainting a wide range of drinking water sources. The current paper centers around water quality contamination by drug toxins, their events, nature, metabolites and their destiny in the climate.