Pharmacokinetic difficulties have been identified as a leading source of novel chemical entity attrition in medication development. The revelation of such difficulties during clinical drug development is connected with high development costs and time investments. Drug clearance, or the elimination of medications from the body, is a fundamental topic in pharmacokinetics, similar to creatinine clearance. The clearance of a medication is rarely assessed directly in clinical practise.
Nitisha Goyal*
Journal of In Silico & In Vitro Pharmacology received 203 citations as per google scholar report