Journal of In Silico & In Vitro Pharmacology

Drug Delivery via Niosomal Noisome

Noisome, also known as non-ionic surfactant vesicles are tiny lamellar structures generated when a non-ionic surfactant of the alkyl or dialkyl polyglycerol ether class is mixed with cholesterol and hydrated in aqueous conditions. They're vesicular structures that look like liposomes and can transport both amphiphilic and lipophilic medicines. The basic method of synthesis is the same, namely, hydration of the lipid phase by an aqueous phase, which can be either a pure surfactant or a surfactant-cholesterol combination. Un-entrapped medication is removed from niosomal dispersion by dialysis centrifugation or gel filtering. Niosomes are vesicles made of synthetic non-ionic surfactants that are unilamellar or multilamellar. They resemble liposomes in appearance. Many pharmacological drugs could benefit from niosomal drug delivery for their effect against various disorders. Niosomes have various advantages, making them a better medication delivery alternative.

Author(s):

Erica Collins

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