Abstract

A Brief Journey of Tocotrienols as Anticancer Agents

The journey of tocotrienol is started when the Vitamin E was first discovered as the fertility factor. Later in the research studies vitamin E was found to be consisting of eight isomers which can be divided into two separate groups known as tocopherols and tocotrienols. The isomers share similarity in structure but differ at much levels based upon their functional or biological properties. Initially tocopherols were investigated much due to their powerful antioxidant properties. However, the other four isomers of tocotrienols were found to be consisting of anticancer properties at varying degree in vitro and in vivo. The mechanisms mediated by tocotrienols such as NFkB pathway, apoptosis, and effect on DNA polymerases are totally different to those of tocopherols.


Author(s):

Kabir I, Rahman M, Rahman K and Islam T



Abstract | Full-Text | PDF

Share this  Facebook  Twitter  LinkedIn  Google+

Recommended Conferences

  • 16th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems
    March 19-21, 2018 Berlin, Germany
  • 4th International Conference on Antibiotics: R&D, B2B April 20-21, 2018 Las Vegas, Nevada, USA
    April 20-21, 2018 Las Vegas, Nevada, USA
  • 1th European Biosimilars Congress April 26-27, 2018 Rome, Italy
    April 26-27, 2018 Rome, Italy
  • 15th Annual European Pharma Congress May 07-09, 2018 Frankfurt, Germany
    May 07-09, 2018 Frankfurt, Germany
Flyer image

Abstracted/Indexed in

  • Google Scholar
  • WorldCat
  • Publons